After graduating from the Gnesin Musical College in 1978, Tatyana Maist joined the troup of the Stanislavsky Drama Theatre. One of her first jobs was to take over the complex title role in Boris Lvov-Anokhin's famous production of that play. She gained fame playing the title role in Anatoly Vasilyev's legendary production of A Young Man's Grown-Up Daughter. During her tenure at the theater, Maist has played the roles of Kira in An Expromptu Fantasy, directed by Alexander Tovstonogov, Militsa in A Melody for a Peacock, directed by Vladimir Portnov, Alina in The Threshold, directed by Vladimir Portnov, Sofya in The Boarders, directed by Vladimir Portnov, and others.
Maist was a member of the creative team on productions of Apples of the Earth and Beautiful Women. VERBATIM at Teatr.doc.In 2007 she played the lead male role in Viktor Alfyorov's Marmelade at Praktika Theatre. She performed in Vladimir Pankov's much talked-about production of Passageway at the Playwright and Director Center. From among her roles in film, Maist singles out: Iron Curtain (directed by Savva Kulish), Smooth Sailing (directed by Boris Khlebnikov), Rusalka (directed by Anna Milikyan), Doc-tor (directed by Vladimir Pankov), and Pelmeny (directed by Gennady Ostrovsky).